P1vital website P1vital fMRI Battery


The P1vital® fMRI system has been used in functional MRI clinical trials by the pharmaceutical industry for over 10 years to help understand how novel compounds for treating CNS Disorders such as schizophrenia and depression affect brain function.

 

Image courtesy of the Oxford Centre for Clinical Magnetic Resonance Research www.ocmr.ox.ac.uk

Image courtesy of the Oxford Centre for Clinical Magnetic Resonance Research www.ocmr.ox.ac.uk

 

The P1vital® fMRI system consists of computer hardware, software, trainer and fMRI compatible response devices provided by Curdes which can be configured to run a number of cognitive tasks including, but not limited to:

 

Task Name Short description Cognitive System Brain area of interest
FACIAL EMOTIONAL PROCESSING TASK (FEP) Affective, Perceptual Amygdala, ACC, Insula, Fusiform
EMOTIONAL COUNTING STROOP (ECS) Affective, Cognitive Control ACC, dlPFC
EMOTIONAL ENCODING (EE) Affective Amygdala
N-BACK TASK (N-BACK) Working Memory, Cognitive Control dlPFC, ACC, Hippocampus, precuneus
MONETARY INCENTIVE DELAY (MID) Reward Striatum, OFC, Insula
MONETARY AND SOCIAL INCENTIVE DELAY TASK (MSID) Reward Striatum, OFC, Insula
AUDIBLE SIGNAL DETECTION TASK (ASD) Perceptual Auditory Cortex, Hippoampus, Insula, left Inferior PFC, ACC
REVERSAL LEARNING TASK (RLT) Reward, Cognitive Control Striatum, OFC, ACC
VIRTUAL MORRIS WATER MAZE TASK (VMWM) Memory Hippocampus, Striatum